1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl or N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride DS Safety Data Sheet ofSupplier Exporter Manufacturers' Representative
Email: info@ammol.orgCall Toll Free +1-855-552-6665
Toll Free: 1-855-55-AMMOL1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl or N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
CAS Number: 25952-53-8
Molecular Formula: C8H17N3-HCl
Molecular Weight: 191.70
1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl or N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochlorideN-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 01-Feb-261. Product Identification
Product Name & Other Names: N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride.
CAS No.: 25952-53-8
EINECS EC Number: 247-361-2
Molecular Weight: 191.70
Chemical Formula: C8H17N3-HCl
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008Acute toxicity, Oral Category 4, H302
Skin irritation Category 2, H315
Serious eye damage Category 1, H318
Specific target organ toxicity (single exposure), Category 3Labeling according Regulation (EC) No 1272/2008
GHS Label Elements
CorrosiveSignal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.Precautionary statements:
P264: Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes.Remove contact lenses, if present and easy to do. Continue rinsing.
P308+313: IF exposed or concerned: Get medical advice/attention.3. Composition/Information on Ingredients
Product Name & Other Names: N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride or 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride.
CAS No.: 25952-53-8
EINECS EC Number: 247-361-24. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Allow the victim to rest in a well-ventilated area. Seek immediate medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes and wash before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention immediately.5. Fire Fighting Measures
Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.6. Accidental Release Measures
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal authority requirements.7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizers, acid anhydrides, acid halides, acids. Store away from sources of heat, moisture. Store at -20C. Shipped with wet ice.8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.9. Physical and Chemical Properties
Appearance: White to Off White Crystalline Powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: 110C - 114C.
Initial boiling point and boiling range: Not available.
Flash point: 73C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Not available.
Viscosity: Not available.
Molecular Weight: 191.70
Chemical Formula: C8H17N3-HCl10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage. Sensitive to moisture.
Hazardous Decomposition Products: When heated to decomposition it emits toxic fumes of nitrogen oxides and hydrogen chloride.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizers, acid anhydrides, acid halides, acids.
Conditions to Avoid: Incompatibles, moisture.11. Toxicological Information
Acute toxicity:
LD50 Oral - Rat female- 500 mg/kg
LD50 Dermal - Rat – 200 to 1000 mg/kg
LD50 Intravenous - Mouse - 56 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC NTP ACGIH OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.12. Ecological Information
Toxicity: The environmental impact of this product has not been fully investigated.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with legal requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: This product does not require a classification for transport.
IMDG/IMO: This product does not require a classification for transport.
IATA/ICAO: This product does not require a classification for transport.15. Regulatory Information
USA:
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA): This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories: Acute health hazard, Chronic Health Hazard. See section 2.
California Proposition 65: This product does not contain any Proposition 65 chemicals.16. Other Information
H302: Harmful if swallowed.
H315: Causes skin irritation.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
**************************American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org
1 February, 2026