American Molecules - Ammol.org USA

alpha-Lipoic Acid or α-Lipoic Acid or Thioctic Acid SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative

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alpha-Lipoic Acid or α-Lipoic Acid or Thioctic Acid
CAS Number: 1077-28-7 or ( also 1200-22-2)

Molecular Formula: C8H14O2S2
Molecular Weight: 206.32

alpha-Lipoic Acid Suppliers
alpha-Lipoic Acid or α-Lipoic Acid or Thioctic Acid

α-Lipoic Acid or alpha-Lipoic Acid or Thioctic Acid SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
 04-Feb-26

1. Product Identification

Product Name & Other Names: α-Lipoic Acid or alpha-Lipoic Acid or Thioctic Acid.
CAS No.: 1077-28-7 or ( also 1200-22-2)
EINECS EC Number: 214-071-2
Molecular Formula: C8H14O2S2
Molecular Weight: 206.32
Relevant uses and uses advised against (if any): Laboratory and Industrial Use.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, oral Category 4, H302
Skin corrosion/irritation Category 2, H315
Skin sensitization, Category 1, H317
Serious eye damage/eye irritation Category 2A, H319
Hazardous to the aquatic environment, long-term hazard Category 2, H411

Labeling according to GHS USA & Regulation (EC) No 1272/2008

GHS Label Elements
Irritant
Irritant
GHS Label Elements
Aquatic Toxicity
Aquatic Toxicity

Signal Words: Warning

Hazard Statements:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H411: Toxic to aquatic life with long lasting effects.

Precautionary Statements:
P264: Wash contaminated parts thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310: IF SWALLOWED: Immediately call a POSION CENTER or doctor/physician.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P403+233+235: Store in a well-ventilated place. Keep container tightly closed. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/national regulation.

3. Composition/Information on Ingredients

Product Name & Other Names: α-Lipoic Acid or alpha-Lipoic Acid or Thioctic Acid.
CAS No.: 1077-28-7 or ( also 1200-22-2)
EINECS EC Number: 214-071-2
Molecular Formula: C8H14O2S2

4. First Aid Measures

Always seek medical attention after first aid measures are provided.

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do not use mouth-to-mouth method if victim inhaled the substance. Induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Get medical attention.
Ingestion: Rinse mouth. Do not induce vomiting without medical advice. If vomiting occurs naturally, have victim lean forward to reduce risk of aspiration. Never give anything by mouth to a victim who is unconscious or is having convulsions. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Use a mild soap if available. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse. For minor skin contact, avoid spreading material on unaffected skin.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

5. Fire Fighting Measures

Products of Combustion: Carbon oxides, sulfur oxides, and toxic fumes.
Fire Extinguishing Media: Water fog. Alcohol foam. Dry chemical. Polymer foam. Dry chemical powder. Carbon dioxide (CO2). Avoid a solid water stream as it may scatter and spread fire. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. In the event of fire and/or explosion do not breathe fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

6. Accidental Release Measures

Personal precautions: Ensure adequate ventilation. Keep people away from and upwind of spill/leak. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Ventilate closed spaces before entering. Keep out of low areas.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not contaminate water.
Methods for containment: Stop leak if you can do so without risk. Move containers to a safe and open area if the leak is irreparable.
Dike the spilled material, where this is possible. Prevent entry into waterways, sewers, basements, or confined areas.
Methods for cleaning up: Clean up in accordance with all applicable regulations. Should not be released into the environment. Dike far ahead of liquid spill for later disposal. Use a non-combustible material like vermiculite, sand, or earth to soak up the product and place into a container for later disposal. Storage: 2C to 8C refrigerate. OK to freeze. Short term shipping may be at ambient temperature. Protect from air and light.

7. Handling and Storage

Precautions for safe handling: Do not handle or store near an open flame, heat, or other sources of ignition. All equipment used when handling the product must be grounded. Use only with adequate ventilation. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: Yellow Crystalline Powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling  point: 243C to 246C literature.
Melting  point/Freezing  point: about 1.29
Flash point: 162C- 163C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility (water): Practically insoluble in water. Slightly soluble in methanol, chloroform and DMSO.
Viscosity: Not available.
Molecular Formula: C8H14O2S2
Molecular Weight: 206.32

10. Stability and Reactivity

Stability: It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits carbon oxides, sulfur oxides, and toxic fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents.
Conditions to Avoid: Avoid light, heat, sparks, open flames and other ignition sources. Contact with incompatible materials.

11. Toxicological Information

Skin: Harmful in contact with skin.
Ingestion: Harmful if swallowed.
Toxicity data:
LD50 Oral - Rat - 1190 mg/kg
Carcinogenicity: Not expected to be hazardous by IARC, OSHA criteria.
Sensitization: May cause sensitization by skin contact.
Mutagenic Effects: No information available
Reproductive Effects: No information available.
Developmental Effects: No information available.
Teratogenicity: No information available.

12. Ecological Information

Toxicity to fish: static test LC50 - Danio rerio (zebra fish) - 43 - 96 mg/l - 96 h
Toxicity to daphnia & other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - ca. 15,1 mg/l - 48 h.
Ecotoxicity: Components of this product have been identified as having potential environmental concerns.
Aquatic toxicity: May cause long-term adverse effects in the aquatic environment. Toxic to aquatic life. Discharge into the environment must be avoided.
Bioaccumulative potential: No information available.
Mobility in soil: No information available.
Results of PBT and vPvB assessment: No information available.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

14. Transport Information

DOT USA, TDG Canada & ADR/RID Europe:
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (alpha-Lipoic Acid)
UN number: 3077; Transport hazard class(es): 9; Packing group: III.
IMDG/IMO & IATA/ICAO:
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (alpha-Lipoic Acid)
UN number: 3077; Transport hazard class(es): 9; Packing group: III.

15. Regulatory Information

USA:
SARA 311/312 Hazards
: Acute Health Hazard. See section 2.
California Prop. 65 Components: Not listed.

Section 16 - Additional Information

European/International Regulations European Labeling in Accordance with EC Directives:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H411: Toxic to aquatic life with long lasting effects.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.

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Suppliers and Manufacturers' Representative:
American Molecules - Ammol.org USA
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org

4 February, 2026