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Dasatinib
CAS Number: 302962-49-8
Molecular Formula: C22H26ClN7O2S
Molecular Weight: 488.01
Dasatinib
Dasatinib SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 24-August-2026
1. Product Identification
Product Name & Other Names: Dasatinib.
CAS No.: 302962-49-8
EINECS EC Code: 801-607-0
Molecular Weight: 488.01
Chemical Formula: C22H26ClN7O2S
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Skin irritation, (Category 2), H315
Serious eye damage (Category 1), H318
Carcinogenicity (Category 2), H351
Reproductive toxicity, (Category 2) H361
Specific target organ toxicity - repeated exposure, (Category 1) Gastro-intestinal system, H372
Chronic aquatic toxicity (Category 1), H410
Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements Health Hazard | GHS Label Elements Corrosive | GHS Label Elements Aquatic Hazard |
Signal Word: Danger
Hazard Statements:
H315 Causes skin irritation.
H318 Causes serious eye damage.
H351 Suspected of causing cancer.
H361 Suspected of damaging fertility. Suspected of damaging the unborn child.
H372 Causes damage to organs (Gastro-intestinal system) through prolonged or repeated exposure.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary Statements
P202: Do not handle until all safety precautions have been read and understood.
P220: Keep/Store away from clothing/other combustible materials.
P221: Take any precaution to avoid mixing with combustibles.
P234 Keep only in original container.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P301+P310+330: IF SWALLOWED: Rinse mouth and immediately call a POISON CENTER or doctor/physician.
P302+P352: IF ON SKIN: Wash with soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P304+P341+P311: IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P314: Get Medical advice/attention if you feel unwell.
P330: If swallowed, rinse mouth.
P308+313: IF exposed or concerned: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P363: Wash contaminated clothing before reuse.
P390: Absorb spillage to prevent material damage.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/regional/national/international regulations.
3. Composition/Information on Ingredients
Product Name & Other Names: Dasatinib.
CAS No.: 302962-49-8
EINECS EC Code: 801-607-0
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, it will cause irritation and damage to the nose and throat. It can cause headaches, bleeding from nose coughing and chest discomfort. Remove the victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: It will cause irritation and burns to mouth, digestive tract and stomach. It may lead to pain, nausea, vomiting, and even collapse. Contact the medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: On contact, it can cause itching, pain, swelling and redness. Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: It can cause severe damage to eyes. Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Fire: Flash point: NA.
Toxic fumes, carbon dioxide, carbon monoxide, sulfur oxides, nitrogen oxides, and chlorine compounds may be formed in fire.
Fire Extinguishing Media: Dry chemical, foam or carbon dioxide and water spray jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Avoid mist formation. Wear full protective equipment and ensure proper ventilation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Vacuum or sweep up and remove to an approved disposal container. Contact Environment Agency.
7. Handling and Storage
Precautions for safe handling: Keep away from heat and source of fire, preferably in a ventilated area. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Keep locked up in tightly closed container. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Do not ingest. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like Oxidizing agents. Better to freeze or refrigerate. May be kept at room temperature between 20C to 25C. Short-term excursions between 15C and 30C are generally acceptable during transit. Keep the container tightly closed to protect it from moisture. Avoid heat. Protect from light. Air Sensitive, Heat Sensitive.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White to off-white powder or crystals.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting point/freezing point: 280C to 286C literature.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Poorly soluble in water. Soluble in DMSO.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: Toxic fumes, carbon dioxide, carbon monoxide, sulfur oxides, nitrogen oxides, and chlorine compounds may be formed in fire when heated to decomposition.
Hazardous Polymerization: Not reported.
Incompatibilities: Oxidizing agents.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles. Protect from light. Air Sensitive, Heat Sensitive.
11. Toxicological Information
Acute oral toxicity: No data found.
Carcinogenicity: Suspected of causing cancer.
Teratogenic Effects: No data found.
Mutagenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: Suspected of damaging the unborn child. Suspected of damaging fertility.
Causes damage to organs through prolonged or repeated exposure - Gastro-intestinal system.
12. Ecological Information
Environmental Toxicity: No data found.
Persistence and Degradability: No data found.
Mobility: No data found.
Bioaccumulation/ Accumulation: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe
UN Number: 3077
Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Dasatinib).
Class: 9, Packing group: III.
IMDG & IATA
UN Number: 3077
Proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Dasatinib).
Class: 9, Packing group: III.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H315 Causes skin irritation.
H318 Causes serious eye damage.
H351 Suspected of causing cancer.
H361 Suspected of damaging fertility. Suspected of damaging the unborn child.
H372 Causes damage to organs (Gastro-intestinal system) through prolonged or repeated exposure.
H410 Very toxic to aquatic life with long lasting effects.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visit Main Page of Dasatinib Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org