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Ramipril SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative |
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Ramipril
CAS Number: 87333-19-5
Molecular Formula: C23H32N2O5
Molecular Weight: 416.52
Ramipril
Ramipril SDS, Safety Data Sheet
MSDS Sheet, Material safety Data Sheet 02-Feb-25
1. Product Identification
Product Name & Other Names: Ramipril.
CAS No.: 87333-19-5
EINECS: EC Number: 642-904-3 or 1312995-182-4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Reproductive toxicity Category 1B, (H360)
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements  Health Hazard |
Signal word: Danger.
Hazard statements:
H360 May damage fertility. May damage the unborn child.
Precautionary statements:
P210: Keep away from heat/sparks/open flames/hot surfaces – No smoking.
P261: Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270: Do not eat, drink, or smoke when using this product.
P280: Wear protective gloves/ eye protection/ face protection.
P305+ P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+313: If exposed or concerned: Get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Ramipril.
CAS No.: 87333-19-5
EINECS: EC Number: 642-904-3 or 1312995-182-4
Molecular Weight: 416.52
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: It is an organic material. Forms explosive mixtures with air on intense heating.
Products of Combustion: It emits Carbon oxides, Nitrogen oxides and fumes when heated.
Fire Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet as it can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Eliminate all sources of ignition. Avoid dust-mist formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled material in a convenient waste disposal container.
Large Spill: Eliminate all sources of ignition. Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Refrigerated (0-10C). Heat Sensitive.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White to almost white powder or crystals.
Odor: No information found.
Odor threshold: No information found.
pH: No information found.
Relative density: No information found.
Boiling Point: 109C literature.
Melting Point: 23C-25C literature.
Flash Point: No information found.
Auto-ignition temperature: No information found.
Decomposition temperature: No information found.
Upper/lower flammability or explosive limits: No information found.
Vapor pressure: No information found.
Vapor density: No information found.
Evaporation rate: No information found.
Flammability (solid, gas): No information found.
Partition coefficient: n-octanol/water: No information found.
Solubility: Soluble in methanol.
Viscosity: No information found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage. Hygroscopic, Air sensitive, Light sensitive. Forms explosive mixtures with air on intense heating.
Hazardous Decomposition Products: It emits Carbon oxides, Nitrogen oxides and fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, Heat.
Conditions to Avoid: Heat, Incompatibles.
11. Toxicological Information
Toxicity to Animals:
ORAL (LD50): >10000 mg/kg (Rat).
Carcinogenic Effects: No information found.
Mutagenic Effects: No information found.
Teratogenic Effects: No information found.
Developmental Toxicity: Damage to fetus possible(N-methyl-2-pyrrolidone).
12. Ecological Information
BOD5 and COD: No information found.
Environmental Toxicity: No information found.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA: Not dangerous goods.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visit Main Page of Ramipril Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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