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Ropinirole HCl or Ropinirole Hydrochloride SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative

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Ropinirole HCl or Ropinirole Hydrochloride
CAS Number: 91374-20-8

Molecular Formula: C16H24N2O
Molecular Weight: 260.38

Ropinirole HCl or Ropinirole Hydrochloride Suppliers
Ropinirole HCl or Ropinirole Hydrochloride

Ropinirole ydrochloride or Ropinirole HCl SDS GHS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
 23-August-2026

1. Product Identification

Product Name & Other Names: Ropinirole Hydrochloride or Ropinirole HCl.
CAS Number: 91374-21-9
EINECS EC Number
: 635-615-9
Molecular Formula
: C16H24N2O
Molecular Weight
: 260.38
Relevant uses and uses advised against (if any): Fracturing and Industrial Manufacturing Use.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral Category 4, H302
Acuate aquatic toxicity (Category 1), H400

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
Aquatic Toxicity
Marine Pollutant
GHS Label Elements
Harmful
Harmful

Signal Words: Danger

Hazard Statements:
H302 Harmful if swallowed.
H400: Very toxic to aquatic life.

Precautionary Statements:
P264: Wash contaminated parts thoroughly after handling.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P281: Use personal protective equipment as required.
P301+330+331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes.

3. Composition/Information on Ingredients

Product Name & Other Names: Ropinirole Hydrochloride or Ropinirole HCl.
CAS Number: 91374-21-9
EINECS EC Number
: 635-615-9

4. First Aid Measures

Always seek medical attention after first aid measures are provided.

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing and shoes before reusing.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush your eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.

5. Fire Fighting Measures

Fire: Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapors is possible in the event of fire. In a fire or if heated, a pressure increase will occur and the container may burst.
Suitable extinguishing media: Water spray, dry powder, foam, carbon dioxide. Avoid solid water streams. Use means suitable for extinguishing surrounding fire.
Products of Combustion: Oxides of carbon, oxides of nitrogen, and toxic fumes will be formed.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of it according to legal requirements.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Product should be worked up in closed equipment as far as possible. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibility: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids, Strong bases. Storage: Keep in a dry place, away from direct light and moisture. Store at room temperature 20C to C. Short-term shipping Temperature may be ambient.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposure belowlow.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, a full face piece particulate respirator (NIOSH type N100 filters) may be worn for up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.

9. Physical and Chemical Properties

Appearance: White or yellowish, crystalline powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting point/freezing point: 241C to 250C. literature.
Initial boiling point and boiling range: Not available.
Flash Point: 93C literature.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Freely soluble in water and in methanol, slightly soluble in ethanol (96 per cent), practically insoluble in heptane.
Viscosity: No data found.

10. Stability and Reactivity

Stability: It is stable under recommended conditions of use and storage. Forms explosive mixtures with air on intense heating. Dust explosion for fine distribution, when whirled up in air.
Hazardous Decomposition Products: Oxides of carbon, oxides of nitrogen, and toxic fumes will be formed.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong bases and strong oxidizing agents.
Conditions to Avoid: Incompatibles, heat, sunlight.

11. Toxicological Information

LD50 oral rat: 396 mg/kg.
Carcinogenicity: Limited evidence of a carcinogenic effect. IARC: 2B - Group 2B.
Reproductive toxicity: Presumed human reproductive toxicant.

12. Ecological Information

Toxicity to fish: LC50 - Pimephales promelas (fathead minnow) - 0,394 mg/l - 96,0 h.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Mobile due to water solubility.
Bioaccumulation/ Accumulation: No data found.
Results of PBT and vPvB assessment: Not PBP and vPvB.

13. Disposal Considerations

Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility.

14. Transport Information

USA DOT & ADR/RID:
Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Ropinirole hydrochloride)
Identification No. UN3077, Hazard Class/Division 9; Packing Group PG III.
IATA & IMDG:
Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Ropinirole hydrochloride)
Identification No. UN3077, Hazard Class/Division 9; Packing Group PG III.

15. Regulatory Information

USA:
SARA 311/312: See section 2.

16. Other Information

European Labeling in Accordance with EC Directives:
H302 Harmful if swallowed.
H400: Very toxic to aquatic life.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.

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Suppliers and Manufacturers' Representative:
American Molecules - Ammol.org USA
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org

23 August, 2026