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Timolol Maleate SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative

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Timolol Maleate
CAS Number: 26921-17-5 or 60469-65-0

Molecular Formula: C13H24N4O3S-C4H4O4
Molecular Weight: 432.49

Timolol Maleate Suppliers
Timolol Maleate

Timolol Maleate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
 02-Feb-25

1. Product Identification

Product Name & Other Names: Timolol Maleate.
CAS Number: 26921-17-5 or 60469-65-0
EINECS EC Number: 248-111-5
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral Category 4, H302
Reproductive toxicity Category 2, H361

Labeling according to GHS USA & Regulation (EC) No 1272/2008

GHS Label Elements
Irritant
Irritant

GHS Label Elements
Health Hazard
Health Hazard

Signal Words: Warning

Hazard Statements:
H302: Harmful if swallowed.
H361: Suspected of damaging fertility or the unborn child.

Precautionary Statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310: IF SWALLOWED: Immediately call a POSION CENTER or doctor/physician.
P314: Get medical advice/attention if you feel unwell.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

3. Composition/Information on Ingredients

Product Name & Other Names: Timolol Maleate.
CAS Number: 26921-17-5 or 60469-65-0
EINECS EC Number: 248-111-5

4. First Aid Measures

Always seek medical attention after first aid measures are provided.

Inhalation: Remove affected person to fresh air; if normal breathing has not returned within a few minutes after exposure, get medical attention.
Skin
: Remove contaminated clothing; wash affected area with soap and water; launder contaminated clothing before reuse. Seek medical attention.
Eyes
: Immediately, flush eyes for 15 minutes in clear running water while holding eyelids open; seek medical attention immediately.
Ingestion: Drink two glasses of water followed by milk, milk of magnesia or other non-alcoholic liquids; Do not induce vomiting; seek medical attention immediately.

5. Fire Fighting Measures

General Hazards: Product will support combustion.
Extinguishing Media: Carbon dioxide, water fog, dry chemical, chemical foam. Keep containers cool by spraying with water. Use extinguishing media appropriate for surrounding fire. Avoid solid water jet as it can scatter the fire.
Fire & Explosion Hazard: May evolve oxides of carbon (COx), nitrogen oxides, sulfur oxides and fumes under fire conditions.
In case of fire, wear a full face positive-pressure self-contained breathing apparatus and protective suit. Self - contained respiratory equipment; cool containers to prevent pressure buildup and explosion when exposed to extreme heat. Caution - material will support combustion!
Unusual Fire and Explosion Hazards: Closed containers can explode due to buildup of pressure when exposed to extreme heat.
Hazardous Combustion Products: Products of combustion include nitrogen oxides, sulfur oxides, CO, CO2 and toxic fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter sewer, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Vacuum or sweep up and remove to an approved disposal container.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Keep containers closed when not in use; protect containers from abuse; protect from extreme temperatures, open flames. Room temperature. Preferably refrigerate.

8. Exposure Controls/Personal Protection

Engineering Controls: The use of local exhaust ventilation is recommended to control emissions near the source. Provide mechanical ventilation of confined spaces. Use corrosion-resistant, explosion-proof ventilation equipment.
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.

9. Physical and Chemical Properties

Appearance: A white or almost white crystals or powder.
Odor: No information found.
Odor threshold: No information found.
pH: 3.8 to 4.3 in 2% solution.
Relative density: No information found.
Melting point/freezing point: 198C literature.
Boiling Point: No information found.
Flash point: No information found.
Auto-ignition temperature: No information found.
Decomposition temperature: No information found.
Upper/lower flammability or explosive limits: No information found.
Vapor Pressure (MM Hg): No information found.
Vapor Density (Air = 1): No information found.
Evaporation Rate: No information found.
Flammability (solid, gas): No information found.
Partition coefficient: n-octanol/water: No information found.
Solubility in Water: Soluble in water and methanol, ethanol (96%). Sparingly soluble in chloroform.
Viscosity: No information found.

10. Stability and Reactivity

Stability: Stable at recommended temperatures and operating conditions.
Conditions to Avoid: Avoid excessively high temperatures, sunlight, air, and incompatibles.
Incompatibilities: Strong oxidizing agents.
Decomposition: Decomposition yields nitrogen oxides, sulfur oxides, carbon monoxide & dioxide, fumes.
Polymerization: Polymerization will not occur.

11. Toxicological Information

Reproduction: Suspected of damaging the unborn child. Suspected of damaging fertility.
Mutagenicity: Not known.
Carcinogenicity: Not listed as a human carcinogen by OSHA, IARC, ACGIH & NTP.
Acute Oral Effects: Oral LD50 – Rats 1028 mg/kg.
Acute Dermal Toxicity: LD50 Dermal - Rat - 3129 mg/kg.

12. Ecological Information

Toxicity to fresh-water fish: No information found.
Persistence and accumulation: No information found.
Mobility: No information found.

13. Disposal Considerations

Dispose in accordance with Local, State, and Federal Regulations. Consult local, state, or Federal Environmental Protection Agency before disposing of any chemicals. Follow all the pollution control rules.

14. Transport Information

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO & IATA/ICAO: Not dangerous goods.

15. Regulatory Information

UNITED STATES REGULATORY INFORMATION
SARA 311/312 Hazard Categories: See section 2.

Section 16 - Additional Information

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visit SDS Safety Data Sheet of Timolol Maleate Suppliers.

American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.

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19 April, 2025