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Tofisopam
CAS Number: 22345-47-7
Molecular Formula: C22H26N2O4
Molecular Weight: 382.46
Tofisopam
Tofisopam SDS GHS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 24-August-2026
1. Product Identification
Product Name & Other Names: Tofisopam.
CAS Number: 22345-47-7
EINECS EC Number: 244-922-3
Molecular Formula: C22H26N2O4
Molecular Weight: 382.46
Relevant uses and uses advised against (if any): Fracturing and Industrial Manufacturing Use.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral Category 4, H302
Acuate aquatic toxicity (Category 1), H400
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements Marine Pollutant | GHS Label Elements Harmful |
Signal Words: Danger
Hazard Statements:
H302 Harmful if swallowed.
H400: Very toxic to aquatic life.
Precautionary Statements:
P264: Wash contaminated parts thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P281: Use personal protective equipment as required.
P301+330+331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes.
3. Composition/Information on Ingredients
Product Name & Other Names: Tofisopam.
CAS Number: 22345-47-7
EINECS EC Number: 244-922-3
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing and shoes before reusing.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush your eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
5. Fire Fighting Measures
Fire: Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapors is possible in the event of fire. In a fire or if heated, a pressure increase will occur and the container may burst.
Suitable extinguishing media: Water spray, dry powder, foam, carbon dioxide. Avoid solid water streams. Use means suitable for extinguishing surrounding fire.
Products of Combustion: Oxides of carbon, oxides of nitrogen, and toxic fumes will be formed.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put into a convenient waste disposal container. Finish cleaning byspreading water on the contaminated surface and dispose of it according to legal requirements.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Product should be worked up in closed equipment as far as possible. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibility: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids, Strong bases. Storage: Keep in a dry place, away from direct light and moisture. Storage: Room Temperature (Recommended in a cool and dark place, <15°C). Light Sensitive.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposure low.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, a full face piece particulate respirator (NIOSH type N100 filters) may be worn for up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White to Light yellow powder or crystals.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting point/freezing point: 152C to 157C literature.
Initial boiling point and boiling range: No data found.
Flash Point: 93C literature.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Practically insoluble in water. Soluble in DMSO.
Viscosity: No data found.
10. Stability and Reactivity
Stability: It is stable under recommended conditions of use and storage. Forms explosive mixtures with air on intense heating. Dust explosion for fine distribution, when whirled up in air.
Hazardous Decomposition Products: Oxides of carbon, oxides of nitrogen, and toxic fumes will be formed.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong bases and strong oxidizing agents.
Conditions to Avoid: Incompatibles, heat, sunlight.
11. Toxicological Information
LD50 oral rat: 825 mg/kg
Carcinogenicity: No data found.
Reproductive toxicity: Presumed human reproductive toxicant.
12. Ecological Information
Toxicity to fish: LC50 - Pimephales promelas (fathead minnow) - 0,929 mg/l - 96,0 h.
Persistence and Degradability: No data found.
Mobility: No data found.
Bioaccumulation/ Accumulation: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
USA DOT & ADR/RID:
Shipping Name: Environmentally hazardous substance, solid n.o.s. (Tofisopam)
Identification No. UN3077, Hazard Class/Division 9; Packing Group PG III.
IATA & IMDG:
Shipping Name: Environmentally hazardous substance, solid n.o.s. (Tofisopam)
Identification No. UN3077, Hazard Class/Division 9; Packing Group PG III.
15. Regulatory Information
USA:
SARA 311/312: See section 2.
16. Other Information
European Labeling in Accordance with EC Directives:
H302 Harmful if swallowed.
H400: Very toxic to aquatic life.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visitMain Page of Tofisopam Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org