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Midazolam SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative |
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Midazolam
CAS Number: 59467-70-8
Molecular Formula: C18H13ClFN3
Molecular Weight: 325.77
Midazolam
Midazolam SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 17-August-2026
1. Product Identification
Product Name & Other Names: Midazolam.
CAS No.: 59467-70-8
EINECS Number: 261-774-5
Molecular Weight: 273.72
Chemical Formula: C18H13ClFN3
Relevant uses and uses advised against (if any): Laboratory Chemicals and Industrial Use only.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute oral toxicity Category 3 H301
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements Toxic |
Signal Word: Danger
Hazard statements:
H301: Toxic if swallowed.
Precautionary statements:
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink, or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a comfortable position for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.
P405: Store locked up.
P501: Dispose of contents/container to authorized agents only.
3. Composition/Information on Ingredients
Product Name & Other Names: Midazolam.
CAS No.: 59467-70-8
EINECS Number: 261-774-5
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used. Wash clothing & Shoes before reuse. Get medical attention.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush your eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
Notes to Physician: Treat symptomatically.
5. Fire Fighting Measures
Fire: Not combustible, however, it can burn at high temperature. Decomposes on heating emitting toxic fumes.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Use means suitable for extinguishing surrounding fire. Avoid heavy water stream. Cool containers with water spray until well after the fire is out. Avoid getting water inside containers.
Decomposition Products: Fumes, hydrogen chloride, chlorine, hydrogen fluoride, fluorine along with nitrogen oxides.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Wear respiratory protection. Avoid breathing vapors, mist, or gas. Ensure adequate ventilation. Keep people away from upwind of spill/leak. Evacuate personnel to safe areas. Pick up and arrange disposal without creating dust. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allowing it to evacuate as per law.
7. Handling and Storage
Do not breathe vapor/dust/mist. Do not get in eyes, on skin, or on clothing. Avoid dust formation. Do not ingest.
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, acid, and bases. Storage: Preserve in tight, light-resistant containers. Preferably refrigerate 2C to 8C.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established.
Engineering Controls: Showers, Eyewash stations, Ventilation systems.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White or yellowish, crystalline powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting Point: 161C to 164C. 158C to 164C is also reported in literature.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), soluble in methanol.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage. Reacts with (some) acids: release of toxic and corrosive gases/vapors (hydrochloric acid, chlorine hydrogen fluoride, fluorine).
Hazardous Decomposition Products: Fumes, hydrogen chloride, chlorine hydrogen fluoride, fluorine along with nitrogen oxides may be released.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidants, acid, and bases.
Conditions to Avoid: Heat, Direct sunlight, Moisture, and Incompatibles. Always avoid Strong acids, Strong alkalis, Oxidizing agents.
11. Toxicological Information
Acute toxicity: Toxic if swallowed.
LD50 Oral, Rat - 215 mg/kg
Carcinogenicity: Not classifiable as to its carcinogenicity to humans by IARC, ACGIH, NTP, or EPA.
Reproductive toxicity: No data found.
Developmental Effects: No data found.
Teratogenicity: No data found.
12. Ecological Information
Toxicity to fish: No data found.
Persistence and Degradability: No data found.
Mobility: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe:
UN number: 2811, Class: 6.1, Packing group: III.
Proper shipping name: Toxic solid, organic, n.o.s. (Midazolam).
IMDG/IMO & IATA/ICAO:
UN number: 2811, Class: 6.1, Packing group: III.
Proper shipping name: Toxic solid, organic, n.o.s. (Midazolam).
15. Regulatory Information
USA:
SARA 311/312 Hazard Categories: See section 2.
California Proposition 65: Not listed.
Section 16 - Additional Information
Labeling according to GHS & Regulation (EC) No 1272/2008
H301: Toxic if swallowed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visit Main Page of Midazolam Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org