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Sitagliptin Phosphate Monohydrate Anhydrous
CAS Number: 654671-77-9 Monohydrate 654671-78-0 Anhydrous
Molecular Formula: C16H20F6N5O6P or C16H15F6N5O•H3PO4-H2O Monohydrate
Molecular Weight: 523.32 Monohydrate
Sitagliptin Phosphate Monohydrate Anhydrous
Sitagliptin Phosphate is the phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.
Sitagliptin Phosphate USP Grade Specifications:
C16H15F6N5O-H3PO4-H2O --- 523.32
C16H15F6N5O-H3PO4 --- 505.31
1,2,4-Triazolo[4,3-a]pyrazine, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-, phosphate (1:1) monohydrate;
7-[(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine monophosphate monohydrate;
(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl-4-(2,4,5-trifluorophenyl)butan-1-on phosphate monohydrate CAS 654671-77-9
UNII: TS63EW8X6F
UNII: QFP0P1DV7Z
DEFINITION
Sitagliptin Phosphate contains NLT 98.0% and NMT 102.0% of sitagliptin phosphate (C16H15F6N5O-H3PO4), calculated on the anhydrous and solvent-free basis.
IDENTIFICATION
A. Infrared Absorption
B. Meets the requirements of the test for Enantiomeric Purity.
C. Identification Tests—General, Phosphate: A solution containing about 40 mg/mL in water meets the requirements of the silver nitrate precipitation tests for orthophosphates.
Organic Impurities: to pass the test by Chromatography.
Water Determination: 3.3% to 3.7%
Sitagliptin Phosphate is also available as pe BP Ph Eur EP monograph.
Please visit SDS Safety Data Sheet of Sitagliptin Phosphate Monohydrate Anhydrous Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org