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Trimetazidine Dihydrochloride or Trimetazidine HCl SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative |
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Trimetazidine Dihydrochloride or Trimetazidine HCl or Trimetazidine Hydrochloride
CAS Number: 13171-25-0
Molecular Formula: C14H24Cl2N2O3
Molecular Weight: 339.26
Trimetazidine Dihydrochloride or Trimetazidine HCl or Trimetazidine Hydrochloride
Trimetazidine Dihydrochloride or Trimetazidine HCl or 1-(2,3,4-Trimethoxybenzyl)piperazine Dihydrochloride SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 23-August-2026
1. Product Identification
Product Name & Other Names: Trimetazidine Dihydrochloride or Trimetazidine HCl or 1-(2,3,4-Trimethoxybenzyl)piperazine Dihydrochloride.
CAS No.: 13171-25-0
EINECS EC Number: 236-117-0
Molecular Weight: 339.26
Chemical Formula: C14H24Cl2N2O3
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4, H302
Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements Irritant |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P501: Dispose of contents/container to authorized agents only.
3. Composition/Information on Ingredients
Product Name & Other Names:Trimetazidine Dihydrochloride or Trimetazidine HCl or 1-(2,3,4-Trimethoxybenzyl)piperazine Dihydrochloride.
CAS No.: 13171-25-0
EINECS EC Number: 236-117-0
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove o fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.
5. Fire Fighting Measures
Fire: May become a fire hazard at high temperatures.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet as it can scatter the fire.
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away rom heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Avoid dust formation and control ignition sources. Storage: Room Preserve in tight, light-resistant containers. Storage: In an airtight container. Room Temperature (Recommended in a cool and dark place, <15°C).
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: In general, dilution ventilation is a satisfactory health hazard control for this substance.
Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White to beige powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Boiling Point: No data found.
Melting Point: 231C to 235C literature.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Freely soluble in water, sparingly soluble in alcohol.
Viscosity: No data found.
10. Stability and Reactivity
Stability: It is stable under recommended conditions of use and storage.
Hazardous Decomposition Products: May produce oxides of nitrogen and carbon along with chlorine compounds and fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flame, ignition sources, light, dusting and incompatibles.
11. Toxicological Information
LD50 oral rat: No data found.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Germ cell mutagenicity: No data found.
Reproductive toxicity: No data found.
12. Ecological Information
Toxicity: Acute Toxicity RAT-ORL LD50: >1700mg/kg.
Persistence and degradability: No data found.
Bioaccumulative potential: No data found.
Mobility: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IATA/ICAO: Not controlled.
IMDG/IMO: Not controlled.
15. Regulatory Information
USA:
SARA 311/312 Hazardous Categorization: See section 2.
California Proposition 65: Not listed.
16. Other Information
European Labeling in Accordance with EC Directives:
H302 Harmful if swallowed
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visit Main Page of Trimetazidine Dihydrochloride or Trimetazidine HCl Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org