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Venlafaxine Hydrochloride or Venlafaxine HCl SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative |
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Venlafaxine Hydrochloride or Venlafaxine HCl
CAS Number: 99300-78-4
Molecular Formula: C17H27NO2-HCl
Molecular Weight: 313.86
Venlafaxine Hydrochloride or Venlafaxine HCl
Venlafaxine Hydrochloride or Venlafaxine HCL SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 29-Jan-25
Section 1: Product and Company Identification
Product Name & Other Names: Venlafaxine Hydrochloride or Venlafaxine HCL.
CAS No.: 99300-78-4
EINECS, EC Number: 200-659-6
Relevant uses and uses advised against (if any): Laboratory chemicals, Manufacture of substances
Supplier: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Specific target organ toxicity - repeated exposure (Category 1), H372
Chronic aquatic toxicity (Category 2), H411
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Health Hazard |
GHS Label Elements |
Signal Words: Danger
Hazard statements:
H372 Causes damage to organs through prolonged or repeated exposure.
H410: Toxic to aquatic life with long lasting effects.
Precautionary statements:
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264 Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+313: IF exposed or concerned: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.
P342+311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
Section 3: Composition / Information on Ingredients
Product Name & Other Names: Venlafaxine Hydrochloride or Venlafaxine HCL.
CAS No.: 99300-78-4
EINECS, EC Number: 200-659-6
Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eyes: Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally.
Skin: Immediately flush skin with excess water for 15 minutes while removing contaminated clothing.
Ingestion: Call Emergency Medical immediately. Rinse mouth with cold water. Give the victim 1-2 cups of water or milk to drink. Induce vomiting immediately.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration.
Section 5: Fire Fighting Measures
It is a non-flammable solid. However, it can burn at high temperature.
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet as it can scatter the fire.
Protective equipment and precautions for firefighters: Use water spray, foam, or dry chemical to extinguish fire. Firefighters should wear full firefighting turn-out gear and respiratory protection. Cool container with water spray.
Special hazards arising from the substance: Hydrogen chloride, carbon oxides, nitrogen oxide and fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Room Temperature. Recommended in a cool and dark place, <15C. Ok to freeze. Light Sensitive.
Section 8: Exposure Controls / Personal Protection
Exposure guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
Section 9: Physical and Chemical Properties
Physical state and appearance: White to almost white powder or crystal.
Odor: No information found.
Odor threshold: No information found.
pH (1% soln/water): No information found.
Relative density: No information found.
Melting Point: 217C literature.
Initial boiling point and boiling range: No information found.
Flash point: No information found.
Auto-ignition temperature: No information found.
Decomposition temperature: No information found.
Upper/lower flammability or explosive limits: No information found.
Vapor pressure: No information found.
Vapor density: No information found.
Evaporation rate: No information found.
Flammability (solid, gas): No information found.
Partition coefficient: n-octanol/water: No information found.
Solubility: Soluble in methanol.
Viscosity: No information found.
Section 10: Stability and Reactivity
Avoid heat and ignition sources.
Stability: Stable under normal conditions of use and storage.
Incompatibility: Heat and strong oxidizing agents. Heat.
Hazardous Decomposition Products: Hydrogen chloride, carbon oxides, nitrogen oxide and fumes.
Hazardous Polymerization: Has not been reported.
Section 11: Toxicology Information
LD50 Oral Rat No information found.
Acute inhalation toxicity: LC50, 4 h, Rat, 4.47 mg/l
Carcinogenicity: No information found.
Reproductive toxicity: No information found.
Developmental Effects: No information found.
Teratogenicity: No information found.
Section 12: Ecological Information
Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna (Water flea) - 38 mg/l - 48 h.
Ecotoxicity (aquatic and terrestrial): Toxic to aquatic life with long lasting effects.
Persistence and Degradability: No information found.
Mobility: No information found.
Results of PBT and vPvB assessment: No information found.
Section 13: Disposal Considerations
Check with all applicable local, regional, and national laws and regulations. Follow all the pollution control rules.
Section 14: Transport Information
DOT USA and ADR/RID Europe:
UN-No: UN3077
Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
Proper technical name: ((Venlafaxine hydrochloride)
Hazard Class: 9; Packing Group: III.
TDG:
UN-No: UN3077
Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
Proper technical name: ((Venlafaxine hydrochloride)
Hazard Class: 9; Packing Group: III.
IATA
UN-No: UN3077
Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
Proper technical name: ((Venlafaxine hydrochloride)
Hazard Class: 9; Packing Group: III.
IMDG/IMO
UN-No: UN3077
Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
Proper technical name: ((Venlafaxine hydrochloride)
Hazard Class: 9; Packing Group: III.
Section 15: Regulatory Information
USA:
SARA 311/312 Hazard Categories: See section 2.
California Proposition 65: Not listed to cause cancer or birth defects or reproductive harm.
Section 16: Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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