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Sodium Methyl Hydroxybenzoate or Methylparaben Sodium USP NF Grade Supplier Exporter Manufacturers' Representative |
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Sodium Methyl Hydroxybenzoate or Methylparaben Sodium or Methyl Paraben Sodium
CAS Number: 5026-62-0
Molecular Formula: C8H7NaO3
Molecular Weight: 174.13
Sodium Methyl Hydroxybenzoate or Methylparaben Sodium or Methyl Paraben Sodium
Methylparaben Sodium USP NF Grade
Methylparaben Sodium contains not less than 98.5 percent and not more than 101.5 percent of C8H7NaO3, calculated on the anhydrous basis.
Completeness of solution: One g of it, dissolved in water, meets the requirement.
Identification:
A: Dissolve 0.5 g in 5 mL of water, acidify with hydrochloric acid, and filter the resulting precipitate. Wash the precipitate with water, and dry it over silica gel for 5 hours: the IR absorption spectrum of a mineral oil dispersion of it exhibits maxima only at the same wavelengths as that of a similar preparation of USP Methylparaben.
B: Ignite about 0.3 g, cool, and dissolve the residue in about 3 mL of 3 N hydrochloric acid. A platinum wire dipped in this solution imparts an intense, persistent yellow color to a nonluminous flame.
pH: between 9.5 and 10.5, in a solution (1 in 1000).
Water: not more than 5.0%.
Chloride: A 0.2-g portion shows no more chloride than corresponds to 0.10 mL of 0.020 N hydrochloric acid (0.035%).
Sulfate: A 0.25-g portion shows no more sulfate than corresponds to 0.30 mL of 0.020 N sulfuric acid (0.12%).
Assay: Gently reflux about 100 mg of Methylparaben Sodium, accurately weighed, with 30 mL of 1 N sodium hydroxide for 30 minutes. Cool, add 25.0 mL of potassium bromate solution (2.78 in 500), 5 mL of potassium bromide solution (1 in 8), and 10 mL of hydrochloric acid, and immediately insert the stopper into the flask. Cool, shake for 15 minutes, and allow to stand for 15 minutes. Quickly add 15 mL of potassium iodide, taking care to avoid the escape of bromine vapor, at once replace the stopper in the flask, and shake vigorously. Rinse the stopper and the neck of the flask with a small quantity of water, and titrate the liberated iodine with 0.1 N sodium thiosulfate, adding 3 mL of starch as the endpoint is approached. [NOTE—About 15 mL is needed.] Perform a blank determination, and note the difference in volumes required. Each mL of the difference in volume of 0.1 N sodium thiosulfate is equivalent to 2.902 mg of C8H7NaO3.
We also supplySodium Methyl Hydroxybenzoate or Methylparaben Sodium or Methyl Paraben Sodium BP Ph Eur Grade.
Please visit SDS Safety Data Sheet of Sodium Methyl Hydroxybenzoate or Methylparaben Sodium or Methyl Paraben Sodium Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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