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Ammonium Glycyrrhizinate or Ammonium Glycyrrhizate
CAS Number: 53956-04-0
Molecular Formula: C42H61O16-NH4
Molecular Weight: 839.96
Ammonium Glycyrrhizinate or Ammonium Glycyrrhizate
Ammonium Glycyrrhizate USP NF Specifications:
C42H62O16-NH3 --- 840.08
Monoammonium glycyrrhizinate;
Glycyrrhizic acid ammonium salt;
α-d-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-d-glucopyranuronosyl-, ammonium salt (1:1);
α-d-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-d-glucopyranuronosyl-, monoammonium salt CAS 53956-04-0
UNII: 3VRD35U26C
UNII: 6FO62043WK
DEFINITION
Ammonium Glycyrrhizate is a mixture of ammonium 18α- and 18β-glycyrrhizate (ammonium salt of (20β)-3β-[[2-O-(β-d-glucopyranosyluronic acid)-α-d-glucopyranosyluronic acid]oxy]-11-oxoolean-12-en-29-oic acid), and the 18β-isomer is the main component. It contains NLT 78.0% and NMT 102.0% of ammonium 18α- and 18β-glycyrrhizate, on the anhydrous basis.
IDENTIFICATION
A. The retention times of the peaks of 18α- and 18β-glycyrrhizic acid from the Sample solution correspond to those from the System suitability solution, as obtained in the Content of Ammonium 18α- and 18β-Glycyrrhizate. [Note— The peak of 18α-glycyrrhizic acid could be absent in the Sample solution.]
B. Identification Tests—General, Ammonium.
Residue on Ignition:
Sample: 1.0 g
Acceptance criteria: NMT 0.5%
Limit of Organic Impurities: To pass the test by chromatography.
Optical Rotation, Specific Rotation:
Sample solution: 10.0 mg/mL of Ammonium Glycyrrhizate in 50% ethanol
Acceptance criteria: +49.0 to +55.0 on the anhydrous basis
Water Determination: Acceptance criteria: NMT 6.0%
Packaging and Storage: Preserve in tight containers, and store in a cool, dry place.
We also offer Ammonium Glycyrrhizinate BP Ph Eur EP Grade as per the monograph.
Please visit SDS Safety Data Sheet of Ammonium Glycyrrhizinate or Ammonium Glycyrrhizate Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org