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Riboflavin or Vitamin B2
CAS Number: 83-88-5
Molecular Formula: C17H20N4O6
Molecular Weight: 376.36
Riboflavin or Vitamin B2
Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. Riboflavin or Vitamin B2 is one of the B vitamins, which are all water soluble. Riboflavin is naturally present in some foods, added to some food products, and available as a dietary supplement. In foods it has an E number of E101, E101(iii).
Riboflavin USP Grade Specifications:
C17H20N4O6 376.36
Riboflavine CAS 83-88-5
UNII: TLM2976OFR
DEFINITION
Riboflavin contains NLT 98.0% and NMT 102.0% of riboflavin (C17H20N4O6), calculated on the dried basis.
IDENTIFICATION
A. Color and Fluorescence of Solution:
Sample solution: 0.01 mg/mL in water
Analysis: Alternately expose to transmitted light and long-wavelength UV light.
Acceptance criteria: The Sample solution is pale greenish yellow by transmitted light. By reflected light, it exhibits an intense yellowish-green fluorescence that disappears upon the addition of mineral acids or alkalies.
Residue on Ignition: NMT 0.3%
Limit of Lumiflavin: To pass the test.
Optical Rotation, Specific Rotation:
Sample solution: 5 mg/mL in 0.05 M carbonate-free sodium hydroxide.
Analysis: Measure the specific rotation within 30 min of preparation.
Acceptance criteria: −115° to −135°
Loss on Drying: Dry 500 mg at 105C for 2 h. It loses NMT 1.5% of its weight.
Riboflavin FCC Food Grade Specifications:
Vitamin B2
C17H20N4O6 Formula weight 376.37
INS: 101(i) CAS 83-88-5
DESCRIPTION
Riboflavin occurs as a yellow to orange-yellow, crystalline powder. When dry, it is not affected by diffused light, but when in solution, light induces deterioration. It melts at about 280C with decomposition, and its saturated solution is neutral to litmus. One-gram dissolves in 3000 to about 20,000 mL of water, the variations being due to differences in the internal crystalline structure. It is less soluble in alcohol than in water. It is insoluble in ether and in chloroform, but it is very soluble in dilute solutions of alkalis.
Function: Nutrient.
Identification: A solution of 1 mg of sample in 100 mL of water is pale green-yellow by transmitted light and has an intense yellow-green fluorescence that disappears on the addition of mineral acids or alkalies.
Assay: Not less than 98.0% and not more than 102.0% of C17H20N4O6, calculated on the dried basis.
Loss on Drying: Not more than 1.5%.
Lumiflavin: Passes test.
Optical (Specific) Rotation: [α]D25°: Between +56.5° and +59.5°, calculated on the dried basis.
Residue on Ignition: Not more than 0.3%.
Riboflavin is available also as per BP Ph Eur monograph.
Please visit SDS Safety Data Sheet of Riboflavin or Vitamin B2 Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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