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Hydrated Sodium Glycerophosphate
CAS Number: 1334-74-3 or 55073-41-1 or 154804-51-0
Molecular Formula: C3H7Na2O6P
Molecular Weight: 216 Anhydrous
Hydrated Sodium Glycerophosphate
Hydrated Sodium Glycerophosphate is not found in USP monograph.
Hydrated Sodium Glycerophosphate BP Ph Eur Grade Specifications
Ph Eur
C3H7Na2O6P-xH2O -- 216.0 (anhydrous substance)
DEFINITION
Mixture of variable proportions of sodium (2RS)-2,3-dihydroxypropyl phosphate and sodium 2-hydroxy-1-(hydroxymethyl)ethyl phosphate. The degree of hydration is 4 to 6.
Content: 98.0 per cent to 102.0 per cent (anhydrous substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or crystals.
Solubility: Freely soluble in water, practically insoluble in acetone and in alcohol.
IDENTIFICATION
A. Solution S (see Tests) gives reaction (a) of sodium.
B. To 0.1 g add 5 ml of dilute nitric acid R. Heat to boiling and boil for 1 min. Cool. The solution gives reaction (b) of phosphates.
C. In a test-tube fitted with a glass tube, mix 0.1 g with 5 g of potassium hydrogen sulphate. Heat strongly and direct the white vapour into 5 ml of decolorised fuchsin solution. A violet-red colour develops which becomes violet upon heating for 30 min on a water-bath.
TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is not more opalescent than reference suspension II (and not more intensely coloured than reference solution.
Alkalinity: To 10 ml of solution S add 0.2 ml of phph solution. Not more than 1.0 ml of 0.1 M hydrochloric acid is required to change the colour of the indicator.
Glycerol and alcohol-soluble substances: Maximum 1.0 per cent.
Shake 1.000 g with 25 ml of alcohol R for 10 min. Filter. Evaporate the filtrate on a water-bath and dry the residue at 70C for 1 h. The residue weighs not more than 10 mg.
Chlorides: Maximum 200 ppm.
Phosphates: Maximum 0.1 per cent.
Sulphates: Maximum 500 ppm.
Iron: Maximum 20 ppm.
Heavy metals: Maximum 20 ppm.
Water: 25.0 per cent to 35.0 per cent, determined on 0.100 g.
Please visit SDS Safety Data Sheet of Hydrated Sodium Glycerophosphate Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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